DRAFT

Announcements

Caltech News: Brain-Machine Interface Device Predicts Internal Speech

Richard Andersen: The History of Neuroscience in Autobiography, Volume 12 Edited by Thomas D. Albright and Larry R. Squire ISBN: 978-0-916110-11-6. <pdf version>

Welcome to Thierri Callier who has joined the lab as a Post-Doc working on Functional Ultrasound.

Welcome to Jennifer Yu who has joined the lab staff as a Software Engineer and SASE Fellow.

New Publications

Whitney S. Griggs, Sumner L. Norman, Thomas Deffieux, Florian Segura, Bruno-Félix Osmanski, Geeling Chau, Vasileios Christopoulos, Charles Liu, Mickael Tanter, Mikhail G. Shapiro, Richard A. Andersen "Decoding Motor Plans Using a Closed-Loop Ultrasonic Brain-Machine Interface" bioRxiv 2022.11.10.515371; doi: https://doi.org/10.1101/2022.11.10.515371 <pdf version>

Sarah K. Wandelt, David A. Bjånes, Kelsie Pejsa, Brian Lee, Charles Liu, Richard A. Andersen "Online internal speech decoding from single neurons in a human participant" medRxiv 2022.11.02.22281775; doi: https://doi.org/10.1101/2022.11.02.22281775 <pdf version>

Guan, C., T. Aflalo, C. Y. Zhang, E. Amoruso, E. R. Rosario, N. Pouratian, R. A. Andersen (2022) "Stability of motor representations after paralysis" eLife 11:e74478. https://doi.org/10.7554/eLife.74478 <pdf version>

Tyson Aflalo, Srinivas Chivukula, Carey Zhang, Emily R. Rosario, Nader Pouratian, Richard A. Andersen "Cognition through internal models: Mirror neurons as one manifestation of a broader mechanism" bioRxiv 2022.09.06.506071; doi: https://doi.org/10.1101/2022.09.06.506071 <pdf version>

Isabelle A. Rosenthal, Luke Bashford, Spencer Kellis, Kelsie Pejsa, Brian Lee, Charles Liu, Richard A. Andersen. "S1 represents multisensory contexts and somatotopic locations within and outside the bounds of the cortical homunculus" bioRxiv 2022.08.29.505313; doi: https://doi.org/10.1101/2022.08.29.505313 <pdf version>

David A. Bjånes, Luke Bashford, Kelsie Pejsa, Brian Lee, Charles Y. Liu, Richard A. Andersen. "Multi-channel intra-cortical micro-stimulation yields quick reaction times and evokes natural somatosensations in a human participant" medRxiv 2022.08.08.22278389; doi: https://doi.org/10.1101/2022.08.08.22278389. <pdf version>

Research

Our behaviors are dictated by our intentions, but we have only recently begun to understand how the brain forms intentions to act. The posterior parietal cortex is situated between the sensory and the movement regions of the cerebral cortex and serves as a bridge from sensation to action. We have found that an anatomical map of intentions exists within this area, with one part devoted to planning eye movements and another part to planning arm movements (Andersen and Buneo 2002). The action plans exist in a cognitive form, specifying the goal of the intended movement.  Current studies involve examining decision making, stages in motor planning, coordinate transformations for sensory guided movements and motion perception.  In recent years we have also used the findings from these animal studies to develop brain-machine interfaces using intention signals recorded from the posterior parietal cortex of tetraplegic human participants (Aflalo et al. 2015).

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