Coding in the Motor System


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Table of contents

Intro

Computing a Voluntary Movements

Reaching movement: Three Functional levels

Major Cortical fields in planing and execution of "purposeful" movements

Frontal motor areas of the cortex

Inputs and Outputs of motor cortex

Input/output of Cortical Motor Areas

Slide 8

The motor Homunculus

Mapping the motor cortical areas by electrical stimulation

Mapping the motor cortical areas by ICMS

Activity of single neurons

First single unit recordings

Evarts experiment:: Effect of load The setup

CTNs Encode FORCE, Not Displacement

BUT: Neurons Code Also for Displacement

Innervation of muscles by Pyramidal tract neurons

Innervation of Muscles by Pyramidal Tract Neurons

Anatomical demonstration of divergent connectivity of PT neurons

Summary of first lectute

Lecture No. 2: Neuronal activity (?continued)

Making movements in "all" directions

Direction tuning

The Population Vector

Testing the First requirement for existence of PV: Tuning curves

Testing the second requirement for existence of PV 2. Distribution of PDs

Testing the Third requirement for existence of PV: Distribution of the model parameters

Population vector

Time Evolution of PV

Rotation of PV

Do single neurg29.htm">Rotation of PV

Do single neuron encode for the "type of movement" ?

"Anticipatory" Activity in MI

Preparation of movement: Set related activity in pre-motor cortex

Set Related Activity During Preparation of Movement

Construction and Coordination of Complex Movements Example: Bimanual Coordination

Loss of Inter-hemispheric Connections Helps in Spatial Decoupling of the Two Hands

SMA lesion: Loss of Bimanual skill (???)

Bimanual coord task

The Bimanual Task Consists of Four Types of Trials

Bimanual related activity

Can we use PV to represent bimanual movements?

Estimating "best fit" for PD in different types of movements

Representation of Bimanual Movements by Population Vectors

Conclusion

Author: Zoltan Nadasdy

E-mail: zoli@md.huji.ac.li@md.huji.ac.il">zoli@md.huji.ac.il

Homepage: http://speedy2.md.huji.ac.il/~zoli/works/

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